Naive and alone, Lino (Piolo Pascual) aimlessly searches for his wife, Mary Grace (Iza Calzado), in the unfamiliar streets of Milan. He meets Jenny (Claudine Barretto), a pragmatic woman who is tired of juggling multiple jobs to provide for her family in the Philippines. She takes Lino under her wing and he gradually learns to cope with the hardships of working abroad while searching for his wife. Weeks go by and yet there are no signs of Mary Grace, compelling Lino to come to terms with his wife abandoning him as well as face the budding feelings between him and Jenny. Their new relationship is put to the test when Jenny finds Mary Grace, now a mother and stuck in a loveless marriage. This leaves Jenny with the difficult burden of telling Lino the truth about his wife or to allow themselves to move on with their own relationship.