How to Follow Strangers has two interconnected stories. The first one is inspired by a true account of a woman who died in her Manhattan apartment and remained there a year before her body was found, decomposing in a crisp Chanel suit. One of the main characters in How To Follow Strangers, a young man named Casey, becomes so obsessed with this urban tragedy that he fakes his own disappearance, wondering if anyone will notice. The second storyline begins when Ellie, a young woman who sees Casey everyday as part of her regular commute actually does notice that he goes missing. When Ellie unintentionally runs into Casey outside of their normal interaction, she begins to follow him, setting off a series of incidents that will bind them together.