With their parents out of town and Megan planning a trip to Denver, Drake and Josh find they'll have the house to themselves for the week. But when they mistakenly put Megan on the wrong flight, they have to take the next plane to Los Angeles to find her. When they arrive, Josh crosses paths with a music producer and convinces him to give Drake a spot on MTV's TRL. But before they can celebrate their good fortune, Drake and Josh stumble upon a counterfeiting scheme and are abducted. With hours to go before Drake is scheduled to perform on TRL, Megan summons the police who rescue Drake and Josh and arrest the criminals. Drake and Josh arrive at the TRL broadcast just in time and Drake performs to a cheering crowd. Having found Megan, our heroes set off to explore Hollywood.