Margherita (Margherita Buy, A FIVE STAR LIFE) is a harried film director who finds that the myriad demands and difficulties of her new movie are starting to commingle with a personal life in crisis. The star of the film, the bombastic American actor Barry Huggins (John Turturro), seems to not know any of his lines and is proving to be a massive headache on the set, and with the crew close to mutiny Margherita is rapidly approaching a meltdown. Away from the shoot, she struggles to cope with her beloved mother's fatal illness and a growing estrangement from her teenage daughter whose life is moving on without her. A funny, touching and highly personal film from Italian master Nanni Moretti (THE SON'S ROOM), MIA MADRE examines themes of loss, memory and the transience of human connection with humor and poignance.